World Class HVAC system
HVAC stands for closely interrelated heat, ventilation and air-conditioning system. HVAC system performs four basic functions:
•Maintains space temperature- Temperature can affect product quality directly as many products are heat sensitive. It can also affect product indirectly by fostering the growth of microbial contaminants on workers.
•Controls airborne particles, dust and microorganism through air filtration using high efficiency particulate air (HEPA) filters.
•Maintains room pressure- Rooms must be kept under a “Positive or Negative” pressure, meaning that air flow between processing room & adjacent area through doors or other openings to reduce airborne contamination. This is achieved by balancing pressure-differential between rooms & adjacent spaces.
•Maintains space moisture (Relative Humidity) – Humidity is controlled by cooling air to dew point temperatures or by using desiccant dehumidifiers. Humidity can affect the efficacy and stability of drugs and is sometimes important to effectively mould the tablets.
Each of the above parameters is controlled and evaluated in light of its potential to impact product quality.